In pharmacy, the effectiveness of a drug largely hinges on the quality and characteristics of its API. The solubility, stability, and bioavailability of an API can significantly affect how well it works in the body. Bioavailability refers to the degree and rate at which an API or active moiety is absorbed and becomes available at the site of action. Therefore, pharmaceutical scientists focus extensively on optimizing these characteristics during the drug formulation process.
The COVID-19 pandemic has also highlighted vulnerabilities in the API supply chain, prompting countries to reassess their dependencies on foreign suppliers. This has led to discussions about promoting local manufacturing of APIs to enhance supply chain resilience.
Moreover, evidence suggests that PQQ may have a profound impact on cognitive function. Studies have shown that supplementation with PQQ can enhance memory, learning, and overall cognitive performance. The benefits are thought to stem from PQQ's ability to stimulate the production of nerve growth factor (NGF), a protein that supports the growth, maintenance, and survival of neurons. This action promotes neurogenesis, the process of forming new neurons, thus creating the potential for regeneration and improved mental agility.